Tuesday, December 23, 2008

Recombinant Equine IL-15

December is finishing up on a high note at Kingfisher Biotech (http://www.kingfisherbiotech.com/). This month, five new proteins for veterinary research have been successfully purified and are being tested for bioactivity - Bovine CCL2, Bovine CXCL9, Bovine IL-2, Equine GM-CSF, and Equine IL-15. These efforts to make more tools available for veterinary research are in part supported by a USDA grant. You can learn more about the grant at http://www.vetimm.org/.

Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells, making it an important molecule to have available for equine research. We successfully purified recombinant equine IL-15 from yeast and will send it out for bioassay in the next week. You can find all the details about our equine Il-15 protein at http://www.kingfisherbiotech.com/.

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