Recombinant Equine CCL2 (MCP-1), CCL3 (MIP-1 alpha), CCL11 (Eotaxin), CXCL9 (MIG), and CXCL10 (IP-10) are now available from Kingfisher Biotech. All five proteins were produced in yeast so they mimic the natural protein.
Chemokines are a family of small cytokines, or proteins secreted by cells. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemotactic cytokines.
Wednesday, April 8, 2009
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