Monday, February 22, 2016

Swine Fas Ligand ELISA

The Swine Fas Ligand (FasL) Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Swine Fas Ligand (FasL) ELISA. The antibodies have been determined to function in an ELISA with the standard provided.

Fas ligand (FasL), also known as CD95L and TNFSF6, is a homotrimeric type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily. FasL plays diverse roles in the immune system, including induction of apoptotic cell death in target cells. FasL-Fas-mediated apoptosis plays fundamental roles in several immune functions. The pathway is involved in functions including regulation of T cell homeostasis and maintenance of immune privilege, apart from its well-established role in T cell-mediated cytotoxicity. Cytotoxicity via the Fas pathway is critical for prevention of pathogenic infections as well as control of tumor cell growth.

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