Bovine CXCL10 (IP-10) ELISA VetSet, 2 Plates

The Bovine CXCL10 (IP-10) VetSet (ELISA Development Kit) is for the quantitative determination of bovine CXCL10 (IP-10) in cell culture supernatants.

Kit Contents

Bovine CXCL10 (IP-10) Coated Plate (2 plates)
Bovine CXCL10 (IP-10) Standard
Bovine CXCL10 (IP-10) Detection Antibody
Streptavidin-HRP

Catalog No.VS1196B-002

C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. 

Canine IL-8 ELISA

Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2.

The Canine IL-8 Do-It-Yourself ELISA from Kingfisher Biotech contains capture antibody, standard, and detection antibody for development of a Canine IL-8 ELISA. The antibodies have been determined to function in an ELISA with the standard provided. 

Component	Quantity	Catalog #
Capture Antibody	100 µg	PB1164B-100
Detection Antibody	50 µg	PBB1165B-050
Standard	5 µg	RP0101D-005

Bovine CCL3 (MIP-1 alpha) Do-It-Yourself ELISA, ≤10 Plates

Chemokine ligand 3 (CCL3), also known as Macrophage inflammatory protein-1 alpha (MIP-1α) is a small cytokine belonging to the CC chemokine family. There are at least 27 distinct members of the C-C subgroup reported for mammals. They are characterized by two adjacent cysteines. CC chemokines induce the migration of monocytes and other cell types such as NK cells and dendritic cells. CCL3 (MIP-1α) is a chemoattractant for several different leukocytes, with varying degrees of potency (monocytes = T-cells>neutrophils>eosinophils).

The Bovine CCL3 (MIP-1α) Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Bovine CCL3 (MIP-1α) ELISA. The antibodies have been determined to function in an ELISA with the standard provided.

Rabbit CCL21 (6Ckine) Do-It-Yourself ELISA

Chemokine ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. It is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC). There are at least 27 distinct members of the C-C subgroup reported for mammals. They are characterized by two adjacent cysteines. CC chemokines induce the migration of monocytes and other cell types such as NK cells and dendritic cells. CCL21 is known to elicit its effects through CCR7.

The Rabbit CCL21 (6Ckine) Do-It-Yourself ELISA (Cat# DIY1121U-003) is the first kit available for the measurement of rabbit CCL21. It contains capture antibody, protein standard, and detection antibody for development of a Rabbit CCL21 (6Ckine) ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Components may also be purchased separately. 

Mouse CXCL5 Recombinant Protein

CXCL5 is a member of the CXC chemokine family and is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines, including IL-1 and TNF-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with IFN-γ. CXCL5 stimulates the chemotaxis of neutrophils. CXCL5 has been shown to play a role in conditions ranging from sun burn to cystitiis and athrosclerosis. 

Kingfisher Biotech's mouse CXCL5 recombinant protein was produced in yeast so it is naturally endotoxin-free.

CCL5 Recombinant Proteins - Bovine, Canine, Chicken, Equne, Guinea Pig, Human, Mouse, Swine

RANTES/CCL5 recombinant proteins can be used in cell culture, as an RANTES/CCL5 ELISA Standard, and as a Western Blot Control. CCL5, also know as RANTES (regulated and normal T cell expressed and secreted) is a member of the C-C Chemokine Family. There are at least 27 distinct members of the C-C subgroup reported for mammals. RANTES (CCL5) is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. CCL5 plays a role in many disease states, including rheumatoid arthritis, HIV, and cancer. CCL5/RANTES recombinant proteins are intended for use in animal model and animal health research.

Bovine CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0062B-025	25 ug
Bovine CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0062B-005	5 ug
Canine CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0454D-025	25 ug
Canine CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0454D-005	5 ug
Chicken CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0982C-025	25 ug
Chicken CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0982C-005	5 ug
Equine CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0070E-025	25 ug
Equine CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0070E-005	5 ug
Guinea Pig CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0348GP-025	25 ug
Guinea Pig CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0348GP-005	5 ug
Human CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0983H-025	25 ug
Human CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0983H-005	5 ug
Mouse CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0984M-025	25 ug
Mouse CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0984M-005	5 ug
Swine CCL5 (RANTES) Recombinant Protein - 100 micrograms	RP0059S-100	100 ug
Swine CCL5 (RANTES) Recombinant Protein - 25 micrograms	RP0059S-025	25 ug
Swine CCL5 (RANTES) Recombinant Protein - 5 micrograms	RP0059S-005	5 ug

IL-8 Across Species

Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. The CXC chemokines described in mammals have been subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Kingfisher Biotech offers IL-8 recombinant proteins from 14 species (bovine, canine, catfish, chicken, dolphin, equine, feline, guinea pig, human, mouse (CXCL12), ovine, rabbit, and swine).

IL-8 Homology Between Species

CCL2 Homology Across 8 Species

Chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemotactic protein-1 (MCP-1), is a small cytokine belonging to the CC chemokine family. There are at least 27 distinct members of the C-C subgroup reported for mammals. They are characterized by two adjacent cysteines. CCL2 (MCP-1) recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. CCL2 (MCP-1) is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis.

MCP-1/CCL2 Homology Across Species

Kingfisher Biotech has Bovine CCL2, Canine CCL2, Equine CCL2, Guinea Pig CCL2, Rabbit CCL2, and Swine CCL2 products, including proteins, antibodies and ELISA VetSets.